- Plans to initiate four Phase 2 trials in second half of 2021
- Exploring additional autoimmune and allergic disease indications for portfolio candidates
Immune Regulation, today announced it is rebranding as Revolo Biotherapeutics (“Revolo Bio”). The new brand, which will be implemented immediately, comes ahead of the advancement of the Company’s drug candidates into five clinical programs, including four Phase 2 trials.
The new brand better reflects the Company’s revolutionary approach to developing therapies that reset the immune system with the goal of achieving superior long-term disease remission for patients with autoimmune and allergic diseases. Revolo Bio’s drug candidates, ‘1805 and ‘1104, have already demonstrated efficacy and safety in both preclinical and human studies while preventing the unwanted effects of chronic immune suppression. Revolo Bio will advance ‘1805 through two Phase 2 trials for patients with moderate-to-severe rheumatoid arthritis and for patients with non-infectious uveitis. Additionally, Revolo Bio is advancing a Phase 2 trial of ‘1104 for patients with eosinophilic esophagitis (EoE) and a Phase 2 allergen sensitivity study. In addition, Revolo Bio recently initiated an additional Phase 1 study of ‘1104 designed to evaluate the safety of ascending doses in healthy volunteers to support future phase 2 clinical trials.
“Revolo Biotherapeutics reflects our focused mission to reset the immune system to achieve long-term disease remission of autoimmune and allergic disease,” said Jonathan Rigby, Group Chief Executive Officer of Revolo Biotherapeutics. “We are advancing four phase 2 clinical programs with multiple near-term readouts occurring, and we believe that the unique, disease-agnostic mechanisms of action of our drug candidates creates vast optionality across multiple indications. Our team of successful industry professionals and immunology and allergic disease experts is rapidly growing to include more dedicated revolutionizers ready to support our upcoming milestones.”
